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KMID : 1155220240490010035
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Journal of the Korean Society of Health Information and Health Statistics
2024 Volume.49 No. 1 p.35 ~ p.45
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Factors Affecting Mortality and Distribution of Co-morbidities in Chronic Obstructive Pulmonary Disease
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Kim Sung-Soo
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Abstract
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Objectives: Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide. This study aims to identify the rules associated with major comorbidities in patients with COPD and analyze how they affect death, thereby suggesting patient management measures that are efficient and can improve the quality of medical care.
Methods: For this purpose, among the Korea Disease Control and Prevention Agency’s discharge injury in-depth survey data of more than 3 million cases from 2006 to 2021, adult patients aged 19 years or older with a principal diagnosis of chronic obstructive pul- monary disease were targeted. χ2-test and independent sample t-test were performed to analyze the distribution of deaths by demographic characteris- tics, and ARM (Association Rule Mining) was analyzed for association rules for comorbidities. Logistic regression analysis was performed on factors influ- encing death.
Results: As a result of the analysis, the mortality rate was high in patients over 75 years of age, patients admitted to the emergency room, and patients discharged from medical institutions with more than 1,000 beds. The prevalence of comorbidities was high for E11 (Type 2 diabetes melli- tus) and I10 (essential hypertension). As a result of analyzing the impact on death based on major association rules, other sepsis (A41) and essential hyper- tension (I10), other sepsis (A41) and pneumonia, organism unspecified (J18), sequelae of tuberculosis (B90) and J96 (respiratory Failure, NEC), sequelae of tuberculosis (B90), and I27 (other pulmonary heart diseases) were found to have a high probability of death.
Conclusions: Based on the major associ- ation rules affecting death, we propose to apply them to a clinical decision support system for efficient patient management and personalized treatment.
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KEYWORD
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Chronic obstructive pulmonary disease, Comorbidity, Association rule, Death factor, Personalized medicine
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